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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 806212Generated: October 31, 2026

tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate → 2-Hydroxymethyl-4-(5-{1-[4-(1-hydroxy-1-methyl-ethyl)-2-trifluoromethyl-benzyl]-1H-indazol-5-ylmethylene}-4-oxo-4,5-dihydro-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/806212

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylateHCID 11106786—
Reactant2-Ethylsulfanyl-5-{1-[4-(1-hydroxy-1-methyl-ethyl)-2-trifluoromethyl-benzyl]-1H-indazol-5-ylmethylene}-thiazol-4-oneHCID 67240215—
Product2-Hydroxymethyl-4-(5-{1-[4-(1-hydroxy-1-methyl-ethyl)-2-trifluoromethyl-benzyl]-1H-indazol-5-ylmethylene}-4-oxo-4,5-dihydro-thiazol-2-yl)-piperazine-1-carboxylic acid tert-butyl esterHCID 77253164—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-1a7e42075b464959b9780a6f2887c63d
Source noteTest data from https://doi.org/10.1039/C8SC04228D