Hexamethylphosphoramide → Ethyl 1-cyclopropyl-7-(2,6-dimethyl-4-pyridinyl)6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

HRID 806378Notes

Reaction equation

[Br:13][c:14]1[c:15]([F:33])[cH:16][c:17]2[c:18](=[O:32])[c:19]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:20][n:21]([CH:24]3[CH2:25][CH2:26]3)[c:22]2[cH:23]1.[CH3:1][c:2]1[n:3][c:4]([CH3:12])[cH:5][c:6]([Sn:8]([CH3:9])([CH3:10])[CH3:11])[cH:7]1.[CH3:34][N:35]([P:36]([N:37]([CH3:38])[CH3:39])([N:40]([CH3:41])[CH3:42])=[O:43])[CH3:44].[O:45]1[CH2:46][CH2:47][O:48][CH2:49][CH2:50]1>>[CH3:1][c:2]1[n:3][c:4]([CH3:12])[cH:5][c:6](-[c:14]2[c:15]([F:33])[cH:16][c:17]3[c:18](=[O:32])[c:19]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:20][n:21]([CH:24]4[CH2:25][CH2:26]4)[c:22]3[cH:23]2)[cH:7]1