4-Bromo-2,6-dimethylpyridine → 3-[1-[4-(2,6-Dimethyl-4-pyridinyl)phenyl]ethyl]-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one
Reaction equation
[Br:35][c:36]1[cH:37][c:38]([CH3:43])[n:39][c:40]([CH3:42])[cH:41]1.[OH:1][CH2:2][CH2:3][CH2:4][C:5]1([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:6][CH2:7][N:8]([CH:12]([CH3:13])[c:14]2[cH:15][cH:16][c:17]([B:20]3[O:21][C:22]([CH3:23])([CH3:24])[C:25]([CH3:26])([CH3:27])[O:28]3)[cH:18][cH:19]2)[C:9](=[O:11])[O:10]1>>[OH:1][CH2:2][CH2:3][CH2:4][C:5]1([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:6][CH2:7][N:8]([CH:12]([CH3:13])[c:14]2[cH:15][cH:16][c:17](-[c:36]3[cH:37][c:38]([CH3:43])[n:39][c:40]([CH3:42])[cH:41]3)[cH:18][cH:19]2)[C:9](=[O:11])[O:10]1Participants
3
Sources & evidence
- ORD record
- ord-1e4faf49a79042da88f471040eee4efd
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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