2-(Methylamino)ethanol → 6-Fluoro-5-{5-[(2-hydroxy-ethyl)-methyl-amino]-pent-1-ynyl}-2,3-dihydro-indole-1-carboxylic acid 4-chloro-phenyl ester

HRID 806498Notes

Reaction equation

HRID 806498 reaction equation
[CH3:31][NH:32][CH2:33][CH2:34][OH:35].[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][c:14]3[cH:15][c:16]([C:21]#[C:22][CH2:23][CH2:24][CH2:25][O:26][S:27]([CH3:28])(=[O:29])=[O:30])[c:17]([F:20])[cH:18][c:19]32)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][c:14]3[cH:15][c:16]([C:21]#[C:22][CH2:23][CH2:24][CH2:25][N:32]([CH3:31])[CH2:33][CH2:34][OH:35])[c:17]([F:20])[cH:18][c:19]32)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 865870136-Fluoro-5-(5-methanesulfonyloxy-pent-1-ynyl)-2,3-dihydro-indole-1-carboxylic acid 4-chloro-phenyl ester

Product 1

HCID 695149196-Fluoro-5-{5-[(2-hydroxy-ethyl)-methyl-amino]-pent-1-ynyl}-2,3-dihydro-indole-1-carboxylic acid 4-chloro-phenyl ester

Sources & evidence

ORD record
ord-1b85fb5897124a96bd99916c20d19589
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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