HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → ethyl 3,5-dimethyl-1-(5-nitro-2-pyridinyl)-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| Reactant | 2-Hydrazinyl-5-nitropyridine | HCID 4031931 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl 3,5-dimethyl-1-(5-nitro-2-pyridinyl)-1H-pyrazole-4-carboxylate | HCID 3545175 | — |
Reaction Steps
Similar to Example 1, equimolar amounts of (5-nitropyridin-2-yl)hydrazine and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. Analysis confirmed synthesis of the named product (m.p. 117° C.–119° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087634B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-3dfffe55f58b4bbcb2b5d2ddd09a9a2a |
| Source note | uspto-grants-2006_08 |