Tris(furan-2-yl)phosphane → N-[[3-[4-[5-[5-(hydroxymethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen-2-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 806501Notes

Reaction equation

HRID 806501 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([C:28]2=[N:29][O:30][CH:31]([CH2:33][OH:34])[CH2:32]2)[s:27]1.[O:1]=[C:2]1[O:3][CH:4]([CH2:17][NH:18][C:19]([CH3:20])=[O:21])[CH2:5][N:6]1[c:7]1[cH:8][cH:9][c:10]([Sn:13]([CH3:14])([CH3:15])[CH3:16])[cH:11][cH:12]1.[o:35]1[cH:36][cH:37][cH:38][c:39]1[P:40]([c:41]1[o:42][cH:43][cH:44][cH:45]1)[c:46]1[o:47][cH:48][cH:49][cH:50]1>>[O:1]=[C:2]1[O:3][CH:4]([CH2:17][NH:18][C:19]([CH3:20])=[O:21])[CH2:5][N:6]1[c:7]1[cH:8][cH:9][c:10](-[c:23]2[cH:24][cH:25][c:26]([C:28]3=[N:29][O:30][CH:31]([CH2:33][OH:34])[CH2:32]3)[s:27]2)[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 521585Tris(furan-2-yl)phosphaneHCID 17954475[3-(5-Bromothien-2-yl)-4,5-dihydroisoxazol-5-yl]methanolHCID 22479436N-[[2-oxo-3-(4-trimethylstannylphenyl)-1,3-oxazolidin-5-yl]methyl]acetamide

Product 1

HCID 10295333N-[[3-[4-[5-[5-(hydroxymethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen-2-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-233868e94a0247a9af6117c5bbdba274
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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