Potassium Cation → tert-Butyl 4-(quinolin-2-yl)piperazine-1-carboxylate

HRID 806668Notes

Reaction equation

HRID 806668 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1.[C:25](=[O:26])([O-:27])[O-:28].[CH3:31][C:32]#[N:33].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1.[K+:29].[K+:30]>>[c:2]1([N:22]2[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23]2)[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 119282-ChloroquinolineHCID 19660Carbonate IonHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 16117834tert-Butyl 4-(quinolin-2-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-a989f7c79fae48e8a6b47fddf2c76352
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…