HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 1-(3-chlorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | m-Chlorophenylhydrazine hydrochloride | HCID 75331 | — |
| Reactant | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(3-chlorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 9965472 | — |
Reaction Steps
Similar to Example 1, equimolar amounts of 3-chlorophenylhydrazine hydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. Analysis confirmed that the resulting solid was determined to be the named product (m.p. 56° C.–57° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087634B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-c9ce789e8e2a4048869aacc55103453f |
| Source note | uspto-grants-2006_08 |