3-Chloro-6-[2-(3-chloro-4-methoxy-phenyl)-ethyl]-6-cyclopentyl-dihydro-pyran-2,4-dione → 6-[2-(3-chloro-4-methoxyphenyl)ethyl]-6-cyclopentyl-4-hydroxy-3-[(4-phenyl-1,3-thiazol-2-yl)thio]-5,6-dihydro-2H-pyran-2-one
Reaction equation
[Cl:1][CH:2]1[C:3](=[O:25])[O:4][C:5]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13]2)([CH2:14][CH2:15][c:16]2[cH:17][c:18]([Cl:24])[c:19]([O:22][CH3:23])[cH:20][cH:21]2)[CH2:6][C:7]1=[O:8].[SH:26][c:27]1[s:28][cH:29][c:30](-[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[n:31]1>>[C:2]1([S:26][c:27]2[s:28][cH:29][c:30](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[n:31]2)=[C:7]([OH:8])[CH2:6][C:5]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13]2)([CH2:14][CH2:15][c:16]2[cH:17][c:18]([Cl:24])[c:19]([O:22][CH3:23])[cH:20][cH:21]2)[O:4][C:3]1=[O:25]Participants
3
Sources & evidence
- ORD record
- ord-1e22a650953b40fb90b887fd467edd1e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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