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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 806888Generated: October 31, 2026

Tetrahydrofuran → 4-Methyl-1-(pyridin-4-yl)-4-(trimethylsilyloxy)pent-2-yn-1-one

https://huagongshe.com/reaction/806888

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant((1,1-Dimethyl-2-propynyl)oxy)trimethylsilaneHCID 87344—
ReactantN-Methoxy-N-methylisonicotinamideHCID 3817473—
ReactantButyllithiumHCID 178418339—
Product4-Methyl-1-(pyridin-4-yl)-4-(trimethylsilyloxy)pent-2-yn-1-oneHCID 59354767—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9356699b70a24881a66cd8990fc37575
Source noteTest data from https://doi.org/10.1039/C8SC04228D