Dichloromethane → 1-(5-Bromo-2-fluorophenyl)-3-(tert-butyldimethylsilyloxy)-2,2-difluoropropan-1-one

HRID 807046Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([F:22])[c:6]([CH:8]([C:9]([CH2:10][O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])([F:19])[F:20])[OH:21])[cH:7]1.[Cl:44][CH2:45][Cl:46].[Cr:23]([O:24][Cr:25]([O-:26])(=[O:27])=[O:28])([O-:29])(=[O:30])=[O:31].[nH+:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[nH+:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:22])[c:6]([C:8]([C:9]([CH2:10][O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])([F:19])[F:20])=[O:21])[cH:7]1