4-(Toluene-4-sulfonyloxymethyl)-cyclohexanecarboxylic acid methyl ester → 4-[5-Chloro-2-(1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-phenoxymethyl]-cyclohexane carboxylic acid methyl ester
Reaction equation
[CH3:27][O:28][C:29](=[O:30])[CH:31]1[CH2:32][CH2:33][CH:34]([CH2:37][O:38][S:39]([c:40]2[cH:41][cH:42][c:43]([CH3:44])[cH:45][cH:46]2)(=[O:47])=[O:48])[CH2:35][CH2:36]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]3)[c:6]([OH:8])[cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:9]2[n:10][c:11]3[c:12]([n:13]2[CH2:14][CH:15]2[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]2)[cH:21][c:22]([F:26])[c:23]([F:25])[cH:24]3)[c:6]([O:8][CH2:37][CH:34]2[CH2:33][CH2:32][CH:31]([C:29]([O:28][CH3:27])=[O:30])[CH2:36][CH2:35]2)[cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f48a9570fa914f98bd114166b41bb069
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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