Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 807075Generated: October 30, 2026

1,2-Dichloroethane → 2-{5-[1-(4-cyano-3-fluorophenyl)-1-hydroxyethyl]imidazol-1-yl}-N-[2-(3'-hydroxybiphenyl-2-yl)ethyl]acetamide

https://huagongshe.com/reaction/807075

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantWaterHCID 962—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
ReactantLithiumHCID 3028194—
Reactant{5-[1-(4-Cyano-3-fluorophenyl)-1-hydroxyethyl]imidazol-1-yl}acetic acidHCID 18433492—
Reactant1-Amino-2-(3'-hydroxybiphenyl-2-yl)ethaneHCID 22627086—
Product2-{5-[1-(4-cyano-3-fluorophenyl)-1-hydroxyethyl]imidazol-1-yl}-N-[2-(3'-hydroxybiphenyl-2-yl)ethyl]acetamideHCID 22627089—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d00f69dbcbbb41ebbb2ce997d5000da2
Source noteTest data from https://doi.org/10.1039/C8SC04228D