2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → N-[3-(1-([2-(Cyanomethoxy)-1-naphthyl]methyl}-4-piperidinyl)phenyl]-2-methylpropanamide
Reaction equation
[CH3:17][CH:18]([C:19](=[O:20])[NH:21][c:22]1[cH:23][c:24]([CH:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]2)[cH:25][cH:26][cH:27]1)[CH3:34].[CH:1](=[O:2])[c:3]1[c:4]([O:13][CH2:14][C:15]#[N:16])[cH:5][cH:6][c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]12>>[CH2:1]([c:3]1[c:4]([O:13][CH2:14][C:15]#[N:16])[cH:5][cH:6][c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]12)[N:31]1[CH2:30][CH2:29][CH:28]([c:24]2[cH:23][c:22]([NH:21][C:19]([CH:18]([CH3:17])[CH3:34])=[O:20])[cH:27][cH:26][cH:25]2)[CH2:33][CH2:32]1Participants
3
Sources & evidence
- ORD record
- ord-a8b169fa3a234501b5c967f128baf83d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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