1,3-Benzodioxole-5-carboxylic acid → Benzo[1,3]dioxole-5-carboxylic acid (4-{2-oxo-2-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethyl}-thiazol-2-yl)-amide

HRID 807131Notes

Reaction equation

HRID 807131 reaction equation
[C:24]([c:25]1[cH:26][c:27]2[c:31]([cH:32][cH:33]1)[O:30][CH2:29][O:28]2)(=[O:34])[OH:35].[NH2:1][c:2]1[s:3][cH:4][c:5]([CH2:7][C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH2:16][C:17]([N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)=[O:23])[CH2:14][CH2:15]2)[n:6]1>>[NH:1]([c:2]1[s:3][cH:4][c:5]([CH2:7][C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([CH2:16][C:17]([N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)=[O:23])[CH2:14][CH2:15]2)[n:6]1)[C:24]([c:25]1[cH:26][c:27]2[c:31]([cH:32][cH:33]1)[O:30][CH2:29][O:28]2)=[O:34]

Participants

3

Reactant 2

HCID 71961,3-Benzodioxole-5-carboxylic acidHCID 596988402-(2-Amino-thiazol-4-yl)-1-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethanone

Product 1

HCID 59698854Benzo[1,3]dioxole-5-carboxylic acid (4-{2-oxo-2-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethyl}-thiazol-2-yl)-amide

Sources & evidence

ORD record
ord-67c309ff44914ac7949de4549f7d7467
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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