3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic Acid → 3-[4-Bromo-5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-pyrazolyl]-propionic acid
Reaction equation
[Br:50][c:51]1[c:52]([CH2:53][CH2:54][CH2:55][OH:56])[n:57][n:58](-[c:59]2[cH:60][cH:61][c:62]([O:63][CH3:64])[cH:65][cH:66]2)[c:67]1-[c:68]1[cH:69][cH:70][c:71]([Cl:72])[cH:73][cH:74]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:6]2[n:7](-[c:8]3[cH:9][cH:10][c:11]([O:12][CH3:13])[cH:14][cH:15]3)[n:16][c:17]([CH2:18][CH2:19][CH2:20][OH:21])[cH:22]2)[cH:23][cH:24]1.[Cl:25][c:26]1[cH:27][cH:28][c:29](-[c:32]2[cH:33][c:34]([CH2:45][CH2:46][C:47](=[O:48])[OH:49])[n:35][n:36]2-[c:37]2[cH:38][cH:39][c:40]([O:43][CH3:44])[cH:41][cH:42]2)[cH:30][cH:31]1>>[Cl:25][c:26]1[cH:27][cH:28][c:29](-[c:32]2[c:33]([Br:50])[c:34]([CH2:45][CH2:46][C:47](=[O:48])[OH:49])[n:35][n:36]2-[c:37]2[cH:38][cH:39][c:40]([O:43][CH3:44])[cH:41][cH:42]2)[cH:30][cH:31]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-61859ea7349e4e788994bfc463ead581
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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