Sodium ion → 2-[1-(2-Chloro-4-morpholin-4-ylfuro[3,2-d]pyrimidin-6-ylmethyl)piperidin-4-yl]propan-2-ol

HRID 807184Notes

Reaction equation

HRID 807184 reaction equation
[C:29]([O:30][BH-:31]([O:32][C:33](=[O:34])[CH3:35])[O:36][C:37](=[O:38])[CH3:39])(=[O:40])[CH3:41].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH:11]=[O:12])[o:10]2.[NH:19]1[CH2:20][CH2:21][CH:22]([C:25]([CH3:26])([CH3:27])[OH:28])[CH2:23][CH2:24]1.[Na+:42]>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:19]1[CH2:20][CH2:21][CH:22]([C:25]([CH3:26])([CH3:27])[OH:28])[CH2:23][CH2:24]1)[o:10]2

Participants

5

Reactant 4

HCID 923Sodium ionHCID 2724942TriacetoxyborohydrideHCID 52003212-(4-Piperidyl)-2-propanolHCID 568337422-Chloro-4-morpholinofuro[3,2-d]pyrimidine-6-carbaldehyde

Product 1

HCID 596060512-[1-(2-Chloro-4-morpholin-4-ylfuro[3,2-d]pyrimidin-6-ylmethyl)piperidin-4-yl]propan-2-ol

Sources & evidence

ORD record
ord-9fa5519884c3460bbb516338e54b765a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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