Dichloromethane → 3-(4-Iodophenyl)-4-cyano-5-ethyl-thiophene-2-carboxylic acid ethyl ester
Reaction equation
[CH2:6]([CH3:7])[O:8][C:9](=[O:10])[c:11]1[s:12][c:13]([S:25]([CH3:26])(=[O:27])=[O:28])[c:14]([C:23]#[N:24])[c:15]1-[c:16]1[cH:17][cH:18][c:19]([I:22])[cH:20][cH:21]1.[CH3:1][CH2:2][Zn:3][CH2:4][CH3:5].[Cl:29][CH2:30][Cl:31]>>[CH2:4]([CH3:5])[c:13]1[s:12][c:11]([C:9]([O:8][CH2:6][CH3:7])=[O:10])[c:15](-[c:16]2[cH:17][cH:18][c:19]([I:22])[cH:20][cH:21]2)[c:14]1[C:23]#[N:24]Participants
4
Sources & evidence
- ORD record
- ord-0939675b76e641d28b81c1c182a4318c
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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