Bromide ion → Ethyl 3-(4-fluorobenzoyl)-4-oxopentanoate

HRID 807514Notes

Reaction equation

HRID 807514 reaction equation
[Br-:27].[Br:20][CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26].[C:14](=[O:15])([O-:16])[O-:17].[CH3:28][CH2:29][CH2:30][CH2:31][N+:32]([CH2:33][CH2:34][CH2:35][CH3:36])([CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH2:43][CH3:44].[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH2:9][C:10]([CH3:11])=[O:12])=[O:13])[cH:6][cH:7]1.[K+:18].[K+:19]>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH:9]([C:10]([CH3:11])=[O:12])[CH2:21][C:22](=[O:23])[O:24][CH2:25][CH3:26])=[O:13])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 259Bromide ionHCID 813Potassium Cation2×HCID 1140TolueneHCID 7748Ethyl bromoacetateHCID 16028TetrabutylammoniumHCID 19660Carbonate IonHCID 4326551-(4-Fluoro-phenyl)-butane-1,3-dione

Product 1

HCID 57444526Ethyl 3-(4-fluorobenzoyl)-4-oxopentanoate

Sources & evidence

ORD record
ord-fdd8469dadec4419b39cf680f6a2364b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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