1-(5-Methyl-4-trifluoromethyl-thiazol-2-yl)-piperazine → (2-Isopropoxy-5-methanesulfonyl-phenyl)-[4-(5-methyl-4-trifluoromethyl-thiazol-2-yl)-piperazin-1-yl]-methanone

HRID 807641Notes

Reaction equation

HRID 807641 reaction equation
[CH3:18][c:19]1[c:20]([C:30]([F:31])([F:32])[F:33])[n:21][c:22]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[s:23]1.[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:8])[OH:9])[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1>>[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:9])[N:27]2[CH2:26][CH2:25][N:24]([c:22]3[n:21][c:20]([C:30]([F:31])([F:32])[F:33])[c:19]([CH3:18])[s:23]3)[CH2:29][CH2:28]2)[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1

Participants

3

Reactant 2

HCID 211001891-(5-Methyl-4-trifluoromethyl-thiazol-2-yl)-piperazineHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 21100244(2-Isopropoxy-5-methanesulfonyl-phenyl)-[4-(5-methyl-4-trifluoromethyl-thiazol-2-yl)-piperazin-1-yl]-methanone

Sources & evidence

ORD record
ord-e68285e4e4bf427a803fd682a5f68e26
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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