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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 807676Generated: October 25, 2026

Hydrochloric Acid → cis-4-[(2-Chloro-5-fluoro-pyridine-3-carbonyl)-amino]-cyclohexanecarboxylic acid benzyl ester

https://huagongshe.com/reaction/807676

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantMethanesulfonic AcidHCID 6395—
ReactantTriethylamineHCID 8471—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant2-Chloro-5-fluoronicotinic acidHCID 11435243—
ReactantBenzyl (1r,4r)-4-aminocyclohexane-1-carboxylateHCID 18646006—
Productcis-4-[(2-Chloro-5-fluoro-pyridine-3-carbonyl)-amino]-cyclohexanecarboxylic acid benzyl esterHCID 20872630—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f4beb7f701fd4bcdae61a08aa4eb8eee
Source noteTest data from https://doi.org/10.1039/C8SC04228D