1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → 3-[3-Fluoro-4-(2-piperidin-1-ylethoxy)phenylamino]-4-naphthalen-2-ylphenol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)[c:15]([F:16])[cH:17]1.[F:18][c:19]1[cH:20][c:21]([NH:34][c:35]2[c:36](-[c:43]3[cH:44][c:45]4[cH:46][cH:47][cH:48][cH:49][c:50]4[cH:51][cH:52]3)[cH:37][cH:38][c:39]([O:41][CH3:42])[cH:40]2)[cH:22][cH:23][c:24]1[O:25][CH2:26][CH2:27][N:28]1[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1>>[F:18][c:19]1[cH:20][c:21]([NH:34][c:35]2[c:36](-[c:43]3[cH:44][c:45]4[cH:46][cH:47][cH:48][cH:49][c:50]4[cH:51][cH:52]3)[cH:37][cH:38][c:39]([OH:41])[cH:40]2)[cH:22][cH:23][c:24]1[O:25][CH2:26][CH2:27][N:28]1[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1Participants
3
Sources & evidence
- ORD record
- ord-fff1b91b9f6143ab91492689125ab723
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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