Acetate → 5-(3,3-Dimethyl-but-1-ynyl)-3-(1,4-dioxa-spiro[4.5]dec-8-ylamino)-thiophene-2-carboxylic acid methyl ester

HRID 807877Notes

Reaction equation

[C:63](=[O:64])([O-:65])[O-:66].[C:87]([O-:88])(=[O:89])[CH3:90].[C:92]([O-:93])(=[O:94])[CH3:95].[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:11]#[C:12][C:13]([CH3:14])([CH3:15])[CH3:16])[cH:8][c:9]1[I:10].[CH3:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1.[Cs+:67].[Cs+:68].[O:69]1[CH2:70][CH2:71][O:72][C:73]12[CH2:74][CH2:75][CH:76]([NH2:79])[CH2:77][CH2:78]2.[Pd+2:91].[cH:17]1[cH:18][cH:19][c:20]([P:21]([c:22]2[cH:23][cH:24][c:25]3[c:26]([cH:27][cH:28][cH:29][cH:30]3)[c:31]2-[c:32]2[c:33]3[c:34]([cH:35][cH:36][cH:37][cH:38]3)[cH:39][cH:40][c:41]2[P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([C:11]#[C:12][C:13]([CH3:14])([CH3:15])[CH3:16])[cH:8][c:9]1[NH:79][CH:76]1[CH2:75][CH2:74][C:73]2([O:69][CH2:70][CH2:71][O:72]2)[CH2:78][CH2:77]1