Acetate → 5-amino-3,4-dihydro-4-hydroxy-4-(trifluoromethyl)-1H-quinolin-2-one
Reaction equation
[CH3:26][CH2:27][OH:28].[H:24][H:25].[K+:23].[NH2:1][c:2]1[c:3]2[c:8]([cH:9][c:10]([Cl:12])[cH:11]1)[NH:7][C:6](=[O:13])[CH2:5][C:4]2([C:14]([F:15])([F:16])[F:17])[OH:18].[O-:19][C:20]([CH3:21])=[O:22]>>[NH2:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[NH:7][C:6](=[O:13])[CH2:5][C:4]2([C:14]([F:15])([F:16])[F:17])[OH:18]Participants
6
Sources & evidence
- ORD record
- ord-a003f291297646af83bc236a34ab00f6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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