2-(1-Ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)-4-hydroxycyclopentanecarboxylic acid tert-butyl ester → 2-(1-Ethoxycarbonyl-2-vinylcyclopropylcarbamoyl)-4-(7-methoxy-8-methyl-2-phenyl-quinazolin-4-yloxy)-cyclopentanecarboxylic acid tert-butyl ester
Reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[CH:28]1[CH:29]([C:34]([NH:35][C:36]2([C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH:37]([CH:39]=[CH2:40])[CH2:38]2)=[O:46])[CH2:30][CH:31]([OH:33])[CH2:32]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([OH:20])[n:8][c:9](-[c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[n:10][c:11]2[c:12]1[CH3:13]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([O:20][CH:31]3[CH2:30][CH:29]([C:34]([NH:35][C:36]4([C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH:37]([CH:39]=[CH2:40])[CH2:38]4)=[O:46])[CH:28]([C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:32]3)[n:8][c:9](-[c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[n:10][c:11]2[c:12]1[CH3:13]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6e8199fbd56a497586e9a264dd2697d9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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