2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetic acid → N-(5-chloro-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide
Reaction equation
[Cl:20][c:21]1[cH:22][c:23](-[c:27]2[n:28][n:29][cH:30][nH:31]2)[c:24]([NH2:26])[s:25]1.[O:1]=[c:2]1[n:3]([CH2:16][C:17](=[O:18])[OH:19])[c:4]2[cH:5][cH:6][c:7]([C:12]([F:13])([F:14])[F:15])[cH:8][c:9]2[cH:10][cH:11]1>>[O:1]=[c:2]1[n:3]([CH2:16][C:17](=[O:19])[NH:26][c:24]2[c:23](-[c:27]3[nH:28][n:29][cH:30][n:31]3)[cH:22][c:21]([Cl:20])[s:25]2)[c:4]2[cH:5][cH:6][c:7]([C:12]([F:13])([F:14])[F:15])[cH:8][c:9]2[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-66d2ea9531774f4b95518cdb87cbf389
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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