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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 808129Generated: October 25, 2026

Acetonitrile → 1-(3,4,5-trimethoxybenzyl)-3-(3-(4-(1-(ethoxycarbonylmethyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)propyl)-3-(4-fluorophenylmethyl)-2-oxopyrrolidine

https://huagongshe.com/reaction/808129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantHydrogen iodideHCID 24841—
Reactant1-(3,4,5-Trimethoxybenzyl)-3-(4-fluorophenylmethyl)-3-(3-methanesulfonyloxypropyl)-2-oxopyrrolidineHCID 18464483—
ReactantEthyl 2-[2-(piperidin-4-ylamino)benzimidazol-1-yl]acetateHCID 22009427—
Product1-(3,4,5-trimethoxybenzyl)-3-(3-(4-(1-(ethoxycarbonylmethyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)propyl)-3-(4-fluorophenylmethyl)-2-oxopyrrolidineHCID 9961842—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bd6ddf0610f04a5db64c8ea11228fcd2
Source noteTest data from https://doi.org/10.1039/C8SC04228D