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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 808140Generated: October 30, 2026

Chlorotrimethylsilane → 3-(5-Nitro-pyridin-2-yl)-azetidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/808140

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorotrimethylsilaneHCID 6397—
Reactant1,2-DibromoethaneHCID 7839—
ReactantTetrahydrofuranHCID 8028—
ReactantPalladiumHCID 23938—
Reactant2-Bromo-5-nitropyridineHCID 78240—
ReactantDibenzylidene acetoneHCID 95417—
ReactantTert-butyl 3-iodoazetidine-1-carboxylateHCID 11000522—
Product3-(5-Nitro-pyridin-2-yl)-azetidine-1-carboxylic acid tert-butyl esterHCID 57470077—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c3dfb6361606468ca49149ef212d4341
Source noteTest data from https://doi.org/10.1039/C8SC04228D