(2-Fluoro-6-methoxyphenyl)boronic acid → 4-amino-N-cyclopropyl-8-(2-fluoro-6-methoxyphenyl)cinnoline-3-carboxamide
Reaction equation
[F:19][c:20]1[c:21]([B:28]([OH:29])[OH:30])[c:22]([O:26][CH3:27])[cH:23][cH:24][cH:25]1.[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH:16]2[CH2:17][CH2:18]2)[n:4][n:5][c:6]2[c:7]([Br:12])[cH:8][cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH:16]2[CH2:17][CH2:18]2)[n:4][n:5][c:6]2[c:7](-[c:21]3[c:20]([F:19])[cH:25][cH:24][cH:23][c:22]3[O:26][CH3:27])[cH:8][cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-35bb72df53314618b56f2d922fb08f0d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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