3-(2-Methoxyethyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-7-amine → {5-Chloro-4-[2-fluoro-6-(tetrahydro-furan-3-yloxy)-phenoxy]-pyrimidin-2-yl}-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl]-amine
Reaction equation
[CH3:23][O:24][CH2:25][CH2:26][N:27]1[CH2:28][CH2:29][c:30]2[c:31]([cH:34][c:35]([NH2:38])[cH:36][cH:37]2)[CH2:32][CH2:33]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:22])[c:6]([O:8][c:9]2[c:10]([F:21])[cH:11][cH:12][cH:13][c:14]2[O:15][CH:16]2[CH2:17][O:18][CH2:19][CH2:20]2)[n:7]1>>[c:2]1([NH:38][c:35]2[cH:34][c:31]3[c:30]([cH:37][cH:36]2)[CH2:29][CH2:28][N:27]([CH2:26][CH2:25][O:24][CH3:23])[CH2:33][CH2:32]3)[n:3][cH:4][c:5]([Cl:22])[c:6]([O:8][c:9]2[c:10]([F:21])[cH:11][cH:12][cH:13][c:14]2[O:15][CH:16]2[CH2:17][O:18][CH2:19][CH2:20]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0502a040dc294152a9f1202774b5dada
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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