Methanol → 1-[3-{4-[(2-amino-4-chlorophenyl)amino]-1-piperidinyl}propyl]-1,3-dihydro-2H-benzimidazol-2-one
Reaction equation
[CH3:33][OH:34].[Cl:1][c:2]1[cH:3][c:4]([N+:28]([O-:29])=[O:30])[c:5]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][CH2:17][n:18]3[c:19](=[O:27])[nH:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[CH2:13][CH2:14]2)[cH:6][cH:7]1.[H:31][H:32]>>[Cl:1][c:2]1[cH:3][c:4]([NH2:28])[c:5]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][CH2:17][n:18]3[c:19](=[O:27])[nH:20][c:21]4[c:22]3[cH:23][cH:24][cH:25][cH:26]4)[CH2:13][CH2:14]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-ac8c8522f6a14e898dc9396c123d2151
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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