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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 808609Generated: October 25, 2026

Pyridine → Ethyl 1-(6-{2-[(4-methoxyphenyl)ethynyl]phenyl}pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate

https://huagongshe.com/reaction/808609

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantTetrabutylammoniumHCID 16028—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantIodide IonHCID 30165—
ReactantTrifluoromethanesulfonic anhydrideHCID 67749—
Reactant1-Ethynyl-4-methoxybenzeneHCID 251020—
ReactantTrifluoromethanesulfonateHCID 2758875—
ReactantEthyl 1-[6-(2-hydroxylphenyl)pyridine-2-yl]-5-trifluoromethyl-1H-pyrazole-4-carboxylateHCID 136298134—
ProductEthyl 1-(6-{2-[(4-methoxyphenyl)ethynyl]phenyl}pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylateHCID 67158916—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8c40ed2100984c84bdf69ade0155b85d
Source noteTest data from https://doi.org/10.1039/C8SC04228D