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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 808617Generated: October 30, 2026

1,2-Dimethoxyethane → [5-(2-amino-6-oxo-3H-purin-9-yl)-3-fluorooxolan-2-yl]methyl 4-[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxy-3-[[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxymethyl]butanoate

https://huagongshe.com/reaction/808617

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantDicyclohexylcarbodiimideHCID 10868—
Reactant4-(Dimethylamino)pyridineHCID 14284—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant2-amino-9-[(2R,4R,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-oneHCID 135525492—
Reactant4-[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxy-3-[[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxymethyl]butanoic acidHCID 178449745—
Product[5-(2-amino-6-oxo-3H-purin-9-yl)-3-fluorooxolan-2-yl]methyl 4-[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxy-3-[[3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]oxymethyl]butanoateHCID 178449746—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-cdb687a6cceb4cf885ad2a40a12dcd99
Source noteTest data from https://doi.org/10.1039/C8SC04228D