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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 808652Generated: October 28, 2026

Tetrahydrofuran → 6-Chloro-2-(2-fluoro-4-trimethylsilanyl-phenylamino)nicotinic acid

https://huagongshe.com/reaction/808652

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant2,6-Dichloronicotinic acidHCID 854047—
ReactantNpc316347HCID 3280088—
Reactant2-Fluoro-4-(trimethylsilyl)anilineHCID 59596599—
Product6-Chloro-2-(2-fluoro-4-trimethylsilanyl-phenylamino)nicotinic acidHCID 59140147—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-dfb8b3a6afe047d68c1f0bc3ce4b7335
Source noteTest data from https://doi.org/10.1039/C8SC04228D