tert-Butyl 2-bromobutanoate → 1,1-Dimethylethyl 2-[[4-cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]butanoate
Reaction equation
[Br:19][CH:20]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:28][CH3:29].[F:1][C:2]([CH2:3][NH:4][c:5]1[cH:6][c:7]([C:13]([F:14])([F:15])[F:16])[c:8]([C:9]#[N:10])[cH:11][cH:12]1)([F:17])[F:18]>>[F:1][C:2]([CH2:3][N:4]([c:5]1[cH:6][c:7]([C:13]([F:14])([F:15])[F:16])[c:8]([C:9]#[N:10])[cH:11][cH:12]1)[CH:20]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:28][CH3:29])([F:17])[F:18]Participants
3
Sources & evidence
- ORD record
- ord-0c706c462938411199157ad31ccfa705
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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