1-Isopropylpiperazine → HCID 131730755, compound

HRID 80869Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([O:14][C:15]([F:18])([F:17])[F:16])=[CH:10][CH:9]=2)=[CH:4][N:3]=1.[CH:19]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)([CH3:21])[CH3:20]>>[ClH:1].[ClH:1].[CH:19]([N:22]1[CH2:27][CH2:26][N:25]([C:2]2[CH:7]=[CH:6][C:5]([C:8]3[CH:13]=[CH:12][C:11]([O:14][C:15]([F:18])([F:17])[F:16])=[CH:10][CH:9]=3)=[CH:4][N:3]=2)[CH2:24][CH2:23]1)([CH3:21])[CH3:20]

Participants

Reactant 2

HCID 780131-Isopropylpiperazine

HCID 87285993HCID 87285993, compound

Product 1

HCID 131730755HCID 131730755, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(4-trifluoromethoxyphenyl)pyridine and 1-isopropylpiperazine.

Sources & evidence

ORD record: ord-bef2287c98fd4303b47ebc27860aee17
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08846677B2

Reaction notes

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