1-Isopropylpiperazine → HCID 131730757, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([F:14])=[CH:12][CH:11]=[CH:10][C:9]=2[F:15])=[CH:4][N:3]=1.[CH:16]([N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([CH3:18])[CH3:17]>>[ClH:1].[ClH:1].[F:15][C:9]1[CH:10]=[CH:11][CH:12]=[C:13]([F:14])[C:8]=1[C:5]1[CH:6]=[CH:7][C:2]([N:22]2[CH2:23][CH2:24][N:19]([CH:16]([CH3:18])[CH3:17])[CH2:20][CH2:21]2)=[N:3][CH:4]=1Participants
3
Procedure
The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(2,6-difluorophenyl)pyridine and 1-isopropylpiperazine.
Sources & evidence
- ORD record
- ord-5cf334cd0df64881a4d0b5db3c48a83d
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08846677B2
Reaction notes
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