1-Isopropylpiperazine → HCID 131730759, compound

HRID 80873Notes

Reaction equation

HRID 80873 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([F:14])[CH:9]=2)=[CH:4][N:3]=1.[CH:15]([N:18]1[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]1)([CH3:17])[CH3:16]>>[ClH:1].[F:14][C:10]1[CH:9]=[C:8]([C:5]2[CH:6]=[CH:7][C:2]([N:21]3[CH2:22][CH2:23][N:18]([CH:15]([CH3:17])[CH3:16])[CH2:19][CH2:20]3)=[N:3][CH:4]=2)[CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 780131-IsopropylpiperazineHCID 202963592-Chloro-5-(3-fluorophenyl)pyridine

Product 1

HCID 131730759HCID 131730759, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(3-fluorophenyl)pyridine and 1-isopropylpiperazine.

Sources & evidence

ORD record
ord-d89d53fd85ea42deb24ff0ae1e352b5a
Source dataset
uspto-grants-2014_09
Patent number
US08846677B2

Reaction notes

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