1-(3-Piperidinopropyl)piperazine → HCID 131730764, compound

HRID 80878Notes

Reaction equation

HRID 80878 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)=[CH:4][N:3]=1.[N:18]1([CH2:24][CH2:25][CH2:26][N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[ClH:1].[ClH:1].[N:18]1([CH2:24][CH2:25][CH2:26][N:27]2[CH2:28][CH2:29][N:30]([C:2]3[CH:7]=[CH:6][C:5]([C:8]4[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=4)=[CH:4][N:3]=3)[CH2:31][CH2:32]2)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]1

Participants

3

Reactant 2

HCID 27372531-(3-Piperidinopropyl)piperazineHCID 508526842-Chloro-5-[4-(trifluoromethyl)phenyl]pyridine

Product 1

HCID 131730764HCID 131730764, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(4-trifluoromethylphenyl)pyridine and 1-(3-piperidinopropyl)piperazine.

Sources & evidence

ORD record
ord-50904cf368b4439984b9a46102108419
Source dataset
uspto-grants-2014_09
Patent number
US08846677B2

Reaction notes

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