5-(3,4-Difluorophenyl)-2-methylthiazole-4-carboxylic acid → HCID 178433005, compound

HRID 808868Notes

Reaction equation

HRID 808868 reaction equation
[CH3:1][CH:2]1[CH2:3][CH:4]2[CH2:5][NH:6][CH:7]([CH2:10][NH:11][C:12](=[O:13])[c:14]3[c:15]([CH3:22])[n:16][c:17]4[s:18][cH:19][cH:20][n:21]34)[CH:8]2[CH2:9]1.[F:23][c:24]1[cH:25][c:26](-[c:31]2[c:32]([C:37](=[O:38])[OH:39])[n:33][c:34]([CH3:36])[s:35]2)[cH:27][cH:28][c:29]1[F:30]>>[CH3:1][CH:2]1[CH2:3][CH:4]2[CH2:5][N:6]([C:37]([c:32]3[c:31](-[c:26]4[cH:25][c:24]([F:23])[c:29]([F:30])[cH:28][cH:27]4)[s:35][c:34]([CH3:36])[n:33]3)=[O:38])[CH:7]([CH2:10][NH:11][C:12](=[O:13])[c:14]3[c:15]([CH3:22])[n:16][c:17]4[s:18][cH:19][cH:20][n:21]34)[CH:8]2[CH2:9]1

Participants

3

Reactant 2

HCID 666395805-(3,4-Difluorophenyl)-2-methylthiazole-4-carboxylic acidHCID 1784324426-methyl-N-[(5-methyl-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[c]pyrrol-3-yl)methyl]imidazo[2,1-b][1,3]thiazole-5-carboxamide

Product 1

HCID 178433005HCID 178433005, compound

Sources & evidence

ORD record
ord-0bb210cc157643bf926592ae623304bb
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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