5-(Methoxycarbonyl)thiophene-2-carboxylic acid → 5-[1-(3-Trifluoromethoxy-phenyl)-ethylcarbamoyl]-thiophene-2-carboxylic acid methyl ester
Reaction equation
[CH3:15][O:16][C:17](=[O:18])[c:19]1[s:20][c:21]([C:24](=[O:25])[OH:26])[cH:22][cH:23]1.[F:1][C:2]([O:3][c:4]1[cH:5][c:6]([CH:10]([CH3:11])[NH2:12])[cH:7][cH:8][cH:9]1)([F:13])[F:14]>>[F:1][C:2]([O:3][c:4]1[cH:5][c:6]([CH:10]([CH3:11])[NH:12][C:24]([c:21]2[s:20][c:19]([C:17]([O:16][CH3:15])=[O:18])[cH:23][cH:22]2)=[O:25])[cH:7][cH:8][cH:9]1)([F:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-3c2715fa50214f0e91fd37ac7383699e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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