4-Amino-1-(1-ethylpropyl)piperidine → [1-(1-Ethylpropyl)piperidin-4-yl]-[6-(4-methanesulfonylphenyl)pyridazin-3-yl]amine

HRID 80890Notes

Reaction equation

HRID 80890 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]([CH3:17])(=[O:16])=[O:15])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1.[NH2:18][CH:19]1[CH2:24][CH2:23][N:22]([CH:25]([CH2:28][CH3:29])[CH2:26][CH3:27])[CH2:21][CH2:20]1>>[CH2:26]([CH:25]([N:22]1[CH2:23][CH2:24][CH:19]([NH:18][C:2]2[N:3]=[N:4][C:5]([C:8]3[CH:13]=[CH:12][C:11]([S:14]([CH3:17])(=[O:16])=[O:15])=[CH:10][CH:9]=3)=[CH:6][CH:7]=2)[CH2:20][CH2:21]1)[CH2:28][CH3:29])[CH3:27]

Participants

3

Reactant 2

HCID 246980774-Amino-1-(1-ethylpropyl)piperidineHCID 435838903-Chloro-6-[4-(methanesulfonyl)phenyl]pyridazine

Product 1

HCID 15951320[1-(1-Ethylpropyl)piperidin-4-yl]-[6-(4-methanesulfonylphenyl)pyridazin-3-yl]amine

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-methanesulfonylphenyl)pyridazine and 4-amino-1-(1-ethylpropyl)piperidine.

Sources & evidence

ORD record
ord-94bed1aa3a5145ddbebe6cc96e5593c9
Source dataset
uspto-grants-2014_09
Patent number
US08846677B2

Reaction notes

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