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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80891Generated: October 30, 2026

1-Isopropylpiperazine → 1-(Propan-2-yl)-4-{5-[4-(trifluoromethyl)phenyl]pyridin-2-yl}piperazine

https://huagongshe.com/reaction/80891

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-IsopropylpiperazineHCID 78013—
Reactant2-Chloro-5-[4-(trifluoromethyl)phenyl]pyridineHCID 50852684—
Product1-(Propan-2-yl)-4-{5-[4-(trifluoromethyl)phenyl]pyridin-2-yl}piperazineHCID 15951382—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 1, starting from 2-chloro-5-(4-trifluoromethylphenyl)pyridine and 1-isopropylpiperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846677B2
Source datasetuspto-grants-2014_09
ORD IDord-9c4983de958244259a53b6a31dbf68c3
Source noteuspto-grants-2014_09