Sodium ion → 3-(5-Difluoromethoxy-4,6-dimethyl-pyridin-2-yl)-7-fluoro-3-(5'-fluoro-[2,3']bipyridinyl-4-yl)-3H-isoindol-1-ylamine

HRID 809018Notes

Reaction equation

[C:41](=[O:42])([O-:43])[O-:44].[CH3:47][O:48][CH2:49][CH2:50][O:51][CH3:52].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]2([c:19]3[n:20][c:21]([CH3:30])[c:22]([O:26][CH:27]([F:28])[F:29])[c:23]([CH3:25])[cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1.[F:31][c:32]1[cH:33][c:34]([B:38]([OH:39])[OH:40])[cH:35][n:36][cH:37]1.[Na+:45].[Na+:46].[cH:53]1[cH:54][cH:55][c:56]([P:57]([Pd:58]([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([P:78]([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[P:97]([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)([c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)[cH:128][cH:129]1>>[c:2]1(-[c:34]2[cH:33][c:32]([F:31])[cH:37][n:36][cH:35]2)[n:3][cH:4][cH:5][c:6]([C:8]2([c:19]3[n:20][c:21]([CH3:30])[c:22]([O:26][CH:27]([F:28])[F:29])[c:23]([CH3:25])[cH:24]3)[N:9]=[C:10]([NH2:18])[c:11]3[c:12]([F:17])[cH:13][cH:14][cH:15][c:16]32)[cH:7]1