HRID80902

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3772

4-Piperidinecarboxamide

C6H12N2O

结构：CC(C)N1CCN(c2ccc(-c3noc(-c4ccc(CCl)cc4)n3)cn2)CC1

HCID15951386

未命名化合物

PRODUCTS

生成物

结构：CC(C)N1CCN(c2ccc(-c3noc(-c4ccc(CN5CCC(C(N)=O)CC5)cc4)n3)cn2)CC1.Cl.Cl

HCID131730774

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a similar procedure to that described in Example 44, starting from 1-(5-(5-(4-chloromethylphenyl)[1,2,4]oxadiazol-3-yl)pyridine-2-yl)-4-isopropylpiperazine and isonipecotamide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2a0917b1d8fb48c4b6287bcee683bb9b
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08846677B2
来源说明: uspto-grants-2014_09

反应 SMILES

[Cl:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:13][N:12]=[C:11]([C:14]3[CH:15]=[CH:16][C:17]([N:20]4[CH2:25][CH2:24][N:23]([CH:26]([CH3:28])[CH3:27])[CH2:22][CH2:21]4)=[N:18][CH:19]=3)[N:10]=2)=[CH:5][CH:4]=1.[NH:29]1[CH2:37][CH2:36][CH:32]([C:33]([NH2:35])=[O:34])[CH2:31][CH2:30]1>>[ClH:1].[ClH:1].[CH:26]([N:23]1[CH2:24][CH2:25][N:20]([C:17]2[N:18]=[CH:19][C:14]([C:11]3[N:10]=[C:9]([C:6]4[CH:5]=[CH:4][C:3]([CH2:2][N:29]5[CH2:37][CH2:36][CH:32]([C:33]([NH2:35])=[O:34])[CH2:31][CH2:30]5)=[CH:8][CH:7]=4)[O:13][N:12]=3)=[CH:15][CH:16]=2)[CH2:21][CH2:22]1)([CH3:28])[CH3:27]