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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 809083Generated: October 26, 2026

Tetrahydrofuran → 3-[3-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-7-yl)-4-trifluoromethoxy-phenyl]-acrylic acid tert-butyl ester

https://huagongshe.com/reaction/809083

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-HCID 81646—
Reactanttert-Butyl DimethylphosphonoacetateHCID 4564495—
Reactant3-(1-ethyl-4,4,6-trimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-7-yl)-4-trifluoromethoxy-benzaldehydeHCID 86611679—
ReactantButyllithiumHCID 178418339—
Product3-[3-(1-Ethyl-4,4,6-trimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-7-yl)-4-trifluoromethoxy-phenyl]-acrylic acid tert-butyl esterHCID 68583252—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9c354d9a6ce747e5abf8565ccc594c16
Source noteTest data from https://doi.org/10.1039/C8SC04228D