N-(2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide → HCID 131730785, compound

HRID 80927Notes

Reaction equation

HRID 80927 reaction equation
[Cl:1][C:2]1[N:3]=[N:4][C:5]([N:8]2[CH2:13][CH2:12][N:11]([CH:14]3[CH2:17][CH2:16][CH2:15]3)[CH2:10][CH2:9]2)=[CH:6][CH:7]=1.[CH3:18][O:19][C:20]1[CH:25]=[C:24](B2OC(C)(C)C(C)(C)O2)[CH:23]=[CH:22][C:21]=1[NH:35][C:36](=[O:38])[CH3:37]>>[ClH:1].[ClH:1].[CH:14]1([N:11]2[CH2:12][CH2:13][N:8]([C:5]3[N:4]=[N:3][C:2]([C:24]4[CH:23]=[CH:22][C:21]([NH:35][C:36](=[O:38])[CH3:37])=[C:20]([O:19][CH3:18])[CH:25]=4)=[CH:7][CH:6]=3)[CH2:9][CH2:10]2)[CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 20817302N-(2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamideHCID 87286249HCID 87286249, compound

Product 1

HCID 131730785HCID 131730785, compound

Procedure

The title compound was prepared by a similar procedure to that described in Example 57, starting from 3-chloro-6-(4-cyclobutyl-piperazin-1-yl)-pyridazine and N-[2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide.

Sources & evidence

ORD record
ord-2f2b83b419794a328769f804e446a4d7
Source dataset
uspto-grants-2014_09
Patent number
US08846677B2

Reaction notes

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