Ethanol → Ethyl 4-(3-methoxyphenyl)piperidine-3-carboxylate

HRID 809279Notes

Reaction equation

HRID 809279 reaction equation
[BH4-:30].[CH3:1][O:2][c:3]1[cH:4][c:5]([CH:9]2[CH2:10][C:11](=[O:20])[NH:12][CH2:13][CH:14]2[C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:6][cH:7][cH:8]1.[CH3:26][O+:27]([CH3:28])[CH3:29].[CH3:32][CH2:33][OH:34].[F:21][B-:22]([F:23])([F:24])[F:25].[Na+:31]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH:14]2[C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:6][cH:7][cH:8]1

Participants

7

Reactant 6

HCID 702EthanolHCID 923Sodium ionHCID 26255TetrafluoroborateHCID 28123BorohydrideHCID 93245TrimethyloxoniumHCID 12947547Ethyl 4-(3-methoxyphenyl)-6-oxopiperidine-3-carboxylate

Product 1

HCID 12947548Ethyl 4-(3-methoxyphenyl)piperidine-3-carboxylate

Sources & evidence

ORD record
ord-ba521086600b4fea969de656d437c360
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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