3-Chloro-6-(3,4-dimethoxyphenyl)pyridazine → HCID 131731891, compound

HRID 80942Notes

Reaction equation

HRID 80942 reaction equation
[Cl:1][C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([O:16][CH3:17])[CH:9]=2)=[CH:6][CH:7]=1.[ClH:18].Cl.[CH2:20]1[NH:25][CH2:24][CH2:23][N:22]2[CH2:26][CH2:27][CH2:28][CH2:29][C@H:21]12>>[ClH:1].[ClH:18].[CH3:17][O:16][C:10]1[CH:9]=[C:8]([C:5]2[N:4]=[N:3][C:2]([N:25]3[CH2:24][CH2:23][N:22]4[CH2:26][CH2:27][CH2:28][CH2:29][C@@H:21]4[CH2:20]3)=[CH:7][CH:6]=2)[CH:13]=[CH:12][C:11]=1[O:14][CH3:15]

Participants

3

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(3,4-dimethoxy-phenyl)-pyridazine and (R)-octahydro-pyrido[1,2-a]-pyrazine, dihydrochloride.

Sources & evidence

ORD record
ord-6f00d4c4ad3c4b56a76c48960aff570a
Source dataset
uspto-grants-2014_09
Patent number
US08846677B2

Reaction notes

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