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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 809488Generated: October 28, 2026

Bicarbonate Ion → N-[4-({3-Bromo-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}methyl)-3-fluorophenyl]-2,2,2-trifluoroacetamide

https://huagongshe.com/reaction/809488

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
Reactant4-Toluenesulfonyl chlorideHCID 7397—
ReactantTetrahydrofuranHCID 8028—
ReactantN-{4-[(3-Bromo-1H-pyrrolo[2,3-b]pyridin-4-yl)methyl]-3-fluorophenyl}-2,2,2-trifluoroacetamideHCID 59305008—
ReactantButyllithiumHCID 178418339—
ProductN-[4-({3-Bromo-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}methyl)-3-fluorophenyl]-2,2,2-trifluoroacetamideHCID 59304989—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-56a7117a715c4839b40c3ee4705a2a05
Source noteTest data from https://doi.org/10.1039/C8SC04228D